Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837787 | 0.87 | GLS (0.54) | ALDH1A1HTTKDM1AKDM4EMEN1 | |
| SCHEMBL13236926 | 0.87 | GLS (0.54) | ALDH1A1HTTKDM1AKDM4EKMT2A | |
| SCHEMBL2194827 | 0.87 | KDM1A (0.57) | ALDH1A1HTTKDM1AKDM4EGLS | |
| SCHEMBL13535201 | 0.87 | VEGFA (0.47) | ALDH1A1HTTKDM1AMEN1KMT2A | |
| SCHEMBL24732680 | 0.86 | PRMT6 (0.54) | ALDH1A1HTTKDM1AKDM4EGLS | |
| SCHEMBL1433538 | 0.86 | FAAH (0.57) | ALDH1A1HTTFAAHKDM1AKDM4E | |
| SCHEMBL266762 | 0.86 | GLS (0.51) | ALDH1A1HTTKDM1AKDM4EGPR119 | |
| SCHEMBL13216758 | 0.86 | MEN1 (0.51) | ALDH1A1HTTFAAHKDM1AKDM4E | |
| SCHEMBL1632715 | 0.86 | KDM4E (0.58) | ALDH1A1HTTFAAHKDM4EMEN1 | |
| SCHEMBL3155717 | 0.86 | MEN1 (0.58) | ALDH1A1HTTFAAHKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817489-A | BACTERICIDES, OR CHEMICAL INTERMEDIATES THEREOF; DRUG LIBRARIES | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | claimed |