Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370837 | 0.90 | NPC1 (0.37) | CUL4AGAANPC1RAB9AMAPT | |
| SCHEMBL8602332 | 0.86 | RORC (0.35) | CUL4AGAANPC1RAB9AMAPT | |
| SCHEMBL7211056 | 0.85 | KDM4E (0.40) | CUL4AGAARAB9AMAPTKDM4E | |
| SCHEMBL17466053 | 0.83 | KDM4E (0.42) | GAANPC1RAB9AMAPTKDM4E | |
| SCHEMBL8600593 | 0.83 | ELANE (0.36) | CUL4AGAANPC1RAB9AMAPT | |
| SCHEMBL8604258 | 0.83 | CUL4A (0.49) | CUL4AGAANPC1RAB9AMAPT | |
| SCHEMBL8076435 | 0.83 | TSHR (0.44) | CUL4AMAPTHPGDLMNATP53 | |
| SCHEMBL6430813 | 0.82 | KDM4E (0.38) | CUL4AGAAMAPTKDM4EHPGD | |
| SCHEMBL7219984 | 0.82 | GAA (0.39) | CUL4AGAANPC1RAB9AMAPT | |
| SCHEMBL8602520 | 0.82 | CUL4A (0.33) | CUL4AGAANPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8169865-A | — | — | None | — | — | JP | disclosed |
| EP-0493606-B1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-1006105-A1 | Benzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-06-07 | — | — | EP | disclosed |
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| JP-H08169865-A | DIHALOPHENYL CARBONATE DERIVATIVE | SAGAMI CHEM RES CENTER | 1996-07-02 | — | — | JP | disclosed |
| US-5464811-A | Benzene derivatives substituted with heterocyclic ring and herbicides containing same as active ingredients | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5424277-A | An N-substituted-3,4,5,6-tetrahydrophthalimide derivative characterized by having a cycloalkoxy group at the 5-position of the phenyl ring on the nitrogen | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |
| EP-0493606-A1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0262428-B1 | HYDANTOIN DERIVATIVES AND HERBICIDES CONTAINING THE DERIVATIVES AS AN ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-08-14 | — | — | EP | disclosed |
| EP-0440319-A1 | Process and intermediates for the preparation of annelated iminothiazoles | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-08-07 | — | — | EP | disclosed |
| US-5017213-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1991-05-21 | — | — | US | disclosed |
| US-4902337-A | Herbicidal hydantoin derivatives | SAGAMI CHEMICAL RESEARCH (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0351641-A1 | 1-Phenylpyrrole | NIHON BAYER AGROCHEM K.K. (JP) | 1990-01-24 | — | — | EP | disclosed |
| EP-0262428-A1 | Hydantoin derivatives and herbicides containing the derivatives as an active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-04-06 | — | — | EP | disclosed |