SCHEMBL854112

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2634258	0.82	BCL2A1 (0.52)	SIRT6LMNAALDH1A1MAPTMEN1
	SCHEMBL4079481	0.81	SIRT6 (0.44)	SIRT6LMNAALDH1A1MAPTMEN1
	SCHEMBL19708633	0.81	ALDH1A1 (0.50)	SIRT6LMNAALDH1A1HPGDMAPT
	SCHEMBL21596389	0.79	SIRT6 (0.67)	SIRT6LMNAALDH1A1MAPTSLC6A2
	SCHEMBL8340776	0.78	L3MBTL1 (0.56)	LMNAHPGDMEN1KMT2ASLC6A2
	SCHEMBL853431	0.78	MAPT (0.53)	LMNAALDH1A1HPGDMAPTMEN1
	SCHEMBL11183530	0.78	MAPT (0.53)	SIRT6LMNAALDH1A1MAPTMEN1
	SCHEMBL31011685	0.78	MAPT (0.56)	SIRT6LMNAALDH1A1MAPTMEN1
	SCHEMBL3974684	0.78	AKR1C3 (0.47)	LMNAALDH1A1HPGDMAPTMEN1
	SCHEMBL28358960	0.78	MEN1 (0.59)	SIRT6LMNAALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.