Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828886 | 0.80 | CA2 (0.38) | METAP1CA1CA2LMNAALDH1A1 | |
| SCHEMBL10489339 | 0.78 | METAP1 (0.39) | METAP1CA1CA2CHRM1AKR1A1 | |
| SCHEMBL27494290 | 0.76 | TDP1 (0.40) | METAP1CA1CA2LMNACHRM1 | |
| SCHEMBL19554546 | 0.76 | DPP4 (0.33) | CA1CA2ALDH1A1 | |
| SCHEMBL17283415 | 0.75 | DPP4 (0.35) | CA1CA2TDP1ALDH1A1TSHR | |
| SCHEMBL18286818 | 0.75 | CA1 (0.33) | METAP1CA1CA2LMNACHRM1 | |
| SCHEMBL27352539 | 0.74 | CA1 (0.43) | METAP1CA1CA2LMNACHRM1 | |
| SCHEMBL28675963 | 0.73 | LMNA (0.38) | METAP1CA1CA2LMNACHRM1 | |
| SCHEMBL4557736 | 0.73 | CHRM1 (0.41) | METAP1CA2LMNACHRM1AKR1A1 | |
| SCHEMBL28436194 | 0.73 | GPR84 (0.42) | CA1CA2CYP3A4GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999059989-A1 | PROCESS FOR THE PREPARATION OF A BENZO FUSED HETEROCYCLO SULFONYL HALIDE INTERMEDIATE | G.D. SEARLE & CO. (US) | 1999-11-25 | — | — | WO | disclosed |