Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546459 | 0.94 | KDM4E (0.38) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8542643 | 0.94 | KDM4E (0.38) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9724759 | 0.92 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8542228 | 0.80 | — | — | |
| SCHEMBL8544532 | 0.76 | KDM4E (0.40) | SMN1; SMN2KDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL2487068 | 0.75 | ATM (0.49) | SMN1; SMN2KDM4EALDH1A1OPRK1NPSR1 | |
| SCHEMBL29833413 | 0.75 | ATM (0.49) | SMN1; SMN2KDM4EALDH1A1OPRK1NPSR1 | |
| SCHEMBL24411329 | 0.74 | SYK (0.37) | NPC1RAB9A | |
| SCHEMBL24955122 | 0.74 | MAPK1 (0.53) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27837816 | 0.73 | OPRK1 (0.47) | KDM4EALDH1A1OPRK1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | claimed |
| EP-0434965-A2 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | claimed |
| US-5026859-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1991-06-25 | — | — | US | claimed |
| JP-4120074-A | — | — | None | — | — | JP | disclosed |
| JP-H04120074-A | 5-HETEROCYCLIC-PYRIDINE-2,3-DICARBOXYLIC ACID ALKYL ESTER, HIRBICIDAL 5-HETEROCYCLIC-2-(2-IMIDAZOLIN-2-YL)PYRIDINE AND THEIR PRODUCTION | AMERICAN CYANAMID CO | 1992-04-21 | — | — | JP | disclosed |