Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541963 | 0.92 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL8542228 | 0.89 | — | — | |
| SCHEMBL8546459 | 0.86 | KDM4E (0.38) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8542643 | 0.86 | KDM4E (0.38) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8544532 | 0.86 | KDM4E (0.40) | SMN1; SMN2KDM4EL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL8545598 | 0.80 | KDM4E (0.38) | SMN1; SMN2KDM4EMAPK1L3MBTL1NPSR1 | |
| SCHEMBL8544867 | 0.80 | KDM4E (0.38) | SMN1; SMN2KDM4EMAPK1L3MBTL1NPSR1 | |
| SCHEMBL2487071 | 0.76 | ATM (0.46) | SMN1; SMN2KDM4EMAPK1L3MBTL1NPSR1 | |
| SCHEMBL29619749 | 0.76 | ATM (0.46) | SMN1; SMN2KDM4EMAPK1L3MBTL1NPSR1 | |
| SCHEMBL8548924 | 0.74 | CNR2 (0.36) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4120074-A | — | — | None | — | — | JP | disclosed |
| JP-H04120074-A | 5-HETEROCYCLIC-PYRIDINE-2,3-DICARBOXYLIC ACID ALKYL ESTER, HIRBICIDAL 5-HETEROCYCLIC-2-(2-IMIDAZOLIN-2-YL)PYRIDINE AND THEIR PRODUCTION | AMERICAN CYANAMID CO | 1992-04-21 | — | — | JP | disclosed |