Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542186 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL8543891 | 0.88 | L3MBTL1 (0.42) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL8543892 | 0.88 | L3MBTL1 (0.42) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL5572235 | 0.81 | GAA (0.50) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL8542113 | 0.80 | KDM4E (0.55) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL27317680 | 0.77 | TPMT (0.55) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL8542090 | 0.74 | KMT2A (0.52) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL9130382 | 0.73 | KDM4E (0.41) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL8542054 | 0.71 | GAA (0.42) | SMN1; SMN2KDM4EHPGDNPC1RAB9A | |
| SCHEMBL3547387 | 0.71 | KDM4E (0.57) | SMN1; SMN2KDM4EHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584085-B1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5554606-A | THIENAMYCIN DERIVATIVES; PSEUDOMONAS | ZENECA LIMITED (GB) | 1996-09-10 | — | — | US | disclosed |
| EP-0584085-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992017479-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD. (GB) | 1992-10-15 | — | — | WO | disclosed |