SCHEMBL5572235

SCHEMBL5572235

C=CCOc1cc(C(=O)O)cc(OCC=C)c1OCC=C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.50
TSHR P16473 1/20 0.50
KDM4E B2RXH2 6/20 0.47
SMN1; SMN2 Q16637 5/20 0.44
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
ALDH1A1 P00352 4/20 0.44
HPGD P15428 3/20 0.44
HTT P42858 3/20 0.44
HSP90AA1 P07900 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 3/20 0.43
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
TP53 P04637 1/20 0.41
FFAR1 O14842 1/20 0.41
LIG1 P18858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8542113 0.92 KDM4E (0.55) GAATSHRKDM4ESMN1; SMN2NPC1
SCHEMBL8542090 0.89 KMT2A (0.52) GAATSHRKDM4ESMN1; SMN2NPC1
SCHEMBL27317680 0.85 TPMT (0.55) GAATSHRKDM4ESMN1; SMN2NPC1
SCHEMBL24983811 0.85 MEN1 (0.54) SMN1; SMN2NPC1RAB9AHPGDMEN1
SCHEMBL29210788 0.85 ALDH1A1 (0.48) GAATSHRKDM4ESMN1; SMN2NPC1
SCHEMBL8542054 0.85 GAA (0.42) GAATSHRKDM4ESMN1; SMN2NPC1
SCHEMBL5824306 0.84 TSHR (0.57) GAATSHRKDM4ESMN1; SMN2ALDH1A1
SCHEMBL19815469 0.84 KDM4E (0.46) GAATSHRKDM4ESMN1; SMN2NPC1
SCHEMBL9130382 0.84 KDM4E (0.41) GAATSHRKDM4ESMN1; SMN2NPC1
SCHEMBL30043932 0.84 MEN1 (0.52) KDM4ESMN1; SMN2NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108192078-B Preparation method of bio-based flame-retardant epoxy resin and bio-based flame-retardant epoxy resin prepared by preparation method 南京大学 2020-04-24 CN claimed
EP-4583845-A1 PROGRAMMABLE STIMULI-RESPONSIVE POLYMERIC FORMULATIONS Ramot at Tel-Aviv University Ltd. (IL) 2025-07-16 EP disclosed
WO-2024052920-A1 PROGRAMMABLE STIMULI-RESPONSIVE POLYMERIC FORMULATIONS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-03-14 WO disclosed
US-11583587-B2 Polymer VECTURA LIMITED 2023-02-21 US disclosed
US-20210138074-A1 POLYMER VECTURA LIMITED (GB) 2021-05-13 US disclosed
EP-3490609-B1 POLYMER VECTURA LTD (GB) 2021-03-31 EP disclosed
CN-108192078-B Preparation method of bio-based flame-retardant epoxy resin and bio-based flame-retardant epoxy resin prepared by preparation method 南京大学 2020-04-24 CN disclosed
EP-3490609-A1 POLYMER Vectura Limited (GB) 2019-06-05 EP disclosed
WO-2018020034-A1 POLYMER VECTURA LIMITED (GB) 2018-02-01 WO disclosed
US-9623046-B2 Amphiphilic Janus-dendrimers THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2017-04-18 US disclosed
US-7279570-B2 Nanoscale discotic liquid crystalline porphyrins KENT STATE UNIVERSITY (US) 2007-10-09 US disclosed
WO-2007081505-A2 NANOSCALE DISCOTIC LIQUID CRYSTALLINE PORPHYRINS KENT STATE UNIVERSITY (US) 2007-07-19 WO disclosed
US-20070151600-A1 NANOSCALE DISCOTIC LIQUID CRYSTALLINE PORPHYRINS KENT STATE UNIVERSITY 2007-07-05 US disclosed
EP-0584085-B1 ANTIBIOTIC CARBAPENEM DERIVATIVES ZENECA LTD (GB) 1998-09-09 EP disclosed
US-5554606-A THIENAMYCIN DERIVATIVES; PSEUDOMONAS ZENECA LIMITED (GB) 1996-09-10 US disclosed
US-5447925-A Carbapenems with side-chain S; use to treat infections IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-09-05 US disclosed
EP-0584085-A1 ANTIBIOTIC CARBAPENEM DERIVATIVES ZENECA LIMITED (GB) 1994-03-02 EP disclosed
EP-0580632-A1 ANTIBIOTIC CARBAPENEM DERIVATIVES ZENECA LIMITED (GB) 1994-02-02 EP disclosed
WO-1992017479-A1 ANTIBIOTIC CARBAPENEM DERIVATIVES ZENECA LTD. (GB) 1992-10-15 WO disclosed
WO-1992017480-A1 ANTIBIOTIC CARBAPENEM DERIVATIVES ZENECA LTD. (GB) 1992-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11583587-B2 Polymer PARP1, PCNA, FCGRT GAA 975/4885TSHR 2231/4885KDM4E 3286/4885
US-20210138074-A1 POLYMER PARP1, PCNA, FCGRT GAA 975/4885TSHR 2231/4885KDM4E 3286/4885
US-20070151600-A1 NANOSCALE DISCOTIC LIQUID CRYSTALLINE PORPHYRINS PPOX, PML, CRY2 GAA 4067/4885TSHR 4155/4885KDM4E 4430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.