Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.51 |
| ▸ | BCHE | P06276 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8542681 | 0.97 | ACHE (0.49) | ACHEBCHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL9587655 | 0.73 | ACHE (0.51) | ACHEBCHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL9875563 | 0.72 | KDM4E (0.68) | ACHEBCHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL8542085 | 0.72 | ACHE (0.50) | ACHEBCHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL8544682 | 0.71 | ACHE (0.49) | ACHEBCHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL8588932 | 0.70 | LTK (0.47) | ACHEALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL8542931 | 0.69 | ACHE (0.50) | ACHEBCHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL8544712 | 0.68 | ACHE (0.49) | ACHEBCHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL9876130 | 0.68 | KDM4E (0.55) | ACHEBCHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL4495989 | 0.67 | KDM4E (0.82) | ACHEBCHEALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179100-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-12 | — | — | US | claimed |
| EP-0560231-B1 | Pyrazolo(3,4-a)acridine derivatives as analgesics | HOECHST MARION ROUSSEL INC (US) | 1998-06-03 | — | — | EP | disclosed |
| EP-0560231-A1 | Pyrazolo(3,4-a)acridine derivatives as analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5179100-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-12 | — | — | US | disclosed |