Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540124 | 0.94 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1HDAC3HDAC1 | |
| SCHEMBL8538241 | 0.91 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1ALOX5ALOX5AP | |
| SCHEMBL8538239 | 0.91 | GPBAR1 (0.67) | CYSLTR1CYSLTR2GPBAR1ALOX5FFAR1 | |
| SCHEMBL9199864 | 0.90 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1HDAC11HDAC8 | |
| SCHEMBL8616407 | 0.85 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2GPBAR1ALOX5ALOX5AP | |
| SCHEMBL8539273 | 0.84 | GPBAR1 (0.65) | CYSLTR1CYSLTR2GPBAR1ALOX5FFAR1 | |
| SCHEMBL8542534 | 0.83 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5FFAR1 | |
| SCHEMBL8615945 | 0.82 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1ALOX5FFAR1 | |
| SCHEMBL3271439 | 0.82 | CYSLTR1 (0.76) | CYSLTR1CYSLTR2GPBAR1ALOX5FFAR1 | |
| SCHEMBL8538426 | 0.81 | CYSLTR1 (0.65) | CYSLTR1CYSLTR2GPBAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539117-B1 | Compounds useful as leukotriene antagonists | LILLY CO ELI (GB) | 1998-03-11 | — | — | EP | disclosed |
| US-5410061-A | Leukotriene antagonist | LILLY INDUSTRIES LIMITED (GB) | 1995-04-25 | — | — | US | disclosed |
| EP-0539117-A1 | Compounds useful as leukotriene antagonists | LILLY INDUSTRIES LIMITED (GB) | 1993-04-28 | — | — | EP | disclosed |