Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537924 | 0.97 | BCHE (0.60) | BCHEACHE | |
| SCHEMBL8539757 | 0.90 | ACHE (0.68) | BCHEACHE | |
| SCHEMBL8543195 | 0.88 | BCHE (0.61) | BCHEACHEFAAH | |
| SCHEMBL9738844 | 0.85 | BCHE (0.51) | BCHEACHELIPEFAAH | |
| Hydrochloric Acid SCHEMBL9671993 | 0.84 | BCHE (0.50) | BCHEACHELIPEFAAH | |
| SCHEMBL8543797 | 0.82 | BCHE (0.62) | BCHEACHELIPEFAAH | |
| SCHEMBL9738702 | 0.82 | BCHE (0.48) | BCHE | |
| Hydrochloric Acid SCHEMBL9671922 | 0.81 | BCHE (0.47) | BCHE | |
| SCHEMBL9672311 | 0.81 | BCHE (0.49) | BCHEACHELIPE | |
| SCHEMBL8543079 | 0.81 | BCHE (0.45) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | claimed |
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |