Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537884 | 0.91 | SMN1; SMN2 (0.50) | MAPTKMT2ARAB9AHPGDMCL1 | |
| SCHEMBL23455576 | 0.81 | KMT2A (0.54) | MAPTKMT2ARAB9AHPGDMCL1 | |
| SCHEMBL30073941 | 0.81 | KMT2A (0.54) | MAPTKMT2ARAB9AHPGDMCL1 | |
| SCHEMBL8541012 | 0.79 | ITGB3 (0.55) | — | |
| SCHEMBL9058448 | 0.73 | POLB (0.79) | MAPTKMT2ARAB9AHPGDMCL1 | |
| SCHEMBL8543801 | 0.71 | MAPT (0.45) | MAPTKMT2ARAB9AHPGDMCL1 | |
| Hydrochloric Acid SCHEMBL8934656 | 0.69 | HPGD (0.60) | KMT2ARAB9AHPGDNPC1POLB | |
| SCHEMBL7495239 | 0.69 | ITGB3 (0.67) | MAPTKMT2ARAB9AHPGDMCL1 | |
| SCHEMBL7495242 | 0.69 | ITGB3 (0.67) | MAPTKMT2ARAB9AHPGDMCL1 | |
| SCHEMBL23455358 | 0.69 | SMN1; SMN2 (0.55) | MAPTKMT2ARAB9AHPGDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |