Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543803 | 0.91 | MAPT (0.47) | SMN1; SMN2LMNAMAPTMCL1RECQL | |
| SCHEMBL8538025 | 0.78 | ITGB3 (0.49) | — | |
| SCHEMBL23455576 | 0.78 | KMT2A (0.54) | SMN1; SMN2LMNAMAPTMCL1RECQL | |
| SCHEMBL30073941 | 0.78 | KMT2A (0.54) | SMN1; SMN2LMNAMAPTMCL1RECQL | |
| SCHEMBL8539600 | 0.76 | MEN1 (0.44) | SMN1; SMN2LMNARAB9ANPC1HPGD | |
| SCHEMBL8542422 | 0.71 | PARP1 (0.36) | SMN1; SMN2MAPTATMTDP1RAB9A | |
| SCHEMBL8541012 | 0.71 | ITGB3 (0.55) | — | |
| SCHEMBL8537881 | 0.70 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMAPTMCL1RECQL | |
| Hydrochloric Acid SCHEMBL8934656 | 0.68 | HPGD (0.60) | SMN1; SMN2RAB9ANPC1KDM4EHPGD | |
| SCHEMBL7498952 | 0.67 | ITGB3 (0.69) | SMN1; SMN2LMNAMAPTMCL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |