Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295116 | 0.89 | PRNP (0.50) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8539034 | 0.83 | PRNP (0.53) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL9397349 | 0.83 | PRNP (0.55) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL1147571 | 0.83 | PRNP (0.60) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8541256 | 0.82 | PRNP (0.54) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL15452534 | 0.82 | PRNP (0.57) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL9402343 | 0.79 | PRNP (0.51) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8539383 | 0.79 | HTT (0.39) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL27295461 | 0.75 | NR4A2 (0.51) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL27303567 | 0.74 | PRNP (0.51) | PRNPRXFP1KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497371-B1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI CHEMICALS INC (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5202329-A | Pyrimidinyloxy(thio)quinoline derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0497371-A1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | disclosed |