SCHEMBL9397349

SCHEMBL9397349

COc1nc(OC)nc(Sc2ccnc3cc(Cl)ccc23)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRNP P04156 2/20 0.55
RXFP1 Q9HBX9 2/20 0.55
POLB P06746 1/20 0.55
KMT2A Q03164 1/20 0.55
KDM4E B2RXH2 1/20 0.50
NR4A2 P43354 2/20 0.44
SOS2 Q07890 1/20 0.44
GAK O14976 1/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 2/20 0.42
NPC1 O15118 1/20 0.42
ABCB1 P08183 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
CYP1A2 P05177 1/20 0.40
TLR8 Q9NR97 1/20 0.40
MAT2A P31153 1/20 0.40
MAPT P10636 1/20 0.39
ATM Q13315 1/20 0.39
CHKA P35790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8541256 0.88 PRNP (0.54) PRNPRXFP1POLBKMT2AKDM4E
SCHEMBL9402343 0.85 PRNP (0.51) PRNPRXFP1POLBKMT2AKDM4E
SCHEMBL9295116 0.84 PRNP (0.50) PRNPRXFP1POLBKMT2AKDM4E
SCHEMBL8544136 0.83 PRNP (0.52) PRNPRXFP1POLBKMT2AKDM4E
SCHEMBL8539034 0.81 PRNP (0.53) PRNPRXFP1POLBKMT2AKDM4E
SCHEMBL1147571 0.81 PRNP (0.60) PRNPRXFP1POLBKMT2AKDM4E
SCHEMBL15452534 0.80 PRNP (0.57) PRNPRXFP1POLBKMT2AKDM4E
SCHEMBL1702115 0.73 LMNA (0.61) PRNPRXFP1POLBKMT2ANR4A2
SCHEMBL27303567 0.71 PRNP (0.51) PRNPRXFP1POLBKMT2AKDM4E
SCHEMBL27295461 0.70 NR4A2 (0.51) PRNPRXFP1POLBKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6041119-A None JP disclosed
JP-H0641119-A TRIAZINYLTHIOQUINOLINE DERIVATIVE AND ITS PRODUCTION AND AGRICULTURAL/HORTICULTURAL GERMICIDE WITH THE SAME AS ACTIVE INGREDIENT MITSUI TOATSU CHEM INC 1994-02-15 JP disclosed