Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.51 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.51 |
| ▸ | PRNP | P04156 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147571 | 0.84 | PRNP (0.60) | NR4A2SOS2PRNPRXFP1KDM4E | |
| SCHEMBL27303567 | 0.81 | PRNP (0.51) | NR4A2SOS2PRNPRXFP1KDM4E | |
| SCHEMBL27306674 | 0.78 | NCF1 (0.46) | MAPTPKML3MBTL1 | |
| SCHEMBL15452534 | 0.77 | PRNP (0.57) | NR4A2SOS2PRNPRXFP1KDM4E | |
| SCHEMBL8544136 | 0.75 | PRNP (0.52) | NR4A2SOS2PRNPRXFP1KDM4E | |
| SCHEMBL4509324 | 0.74 | TLR8 (0.59) | NR4A2SOS2KMT2ACYP1A2MAPT | |
| SCHEMBL4355081 | 0.72 | NR4A2 (0.61) | NR4A2SOS2KMT2ACYP1A2MAPT | |
| SCHEMBL7464813 | 0.72 | NR4A2 (0.53) | NR4A2SOS2PRNPRXFP1KDM4E | |
| SCHEMBL9452123 | 0.71 | MAPT (0.74) | NR4A2KMT2APOLBCYP1A2MAPT | |
| SCHEMBL7456971 | 0.71 | NR4A2 (0.51) | NR4A2SOS2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1034925-A | Quinoline, quinazoline and cinnoline | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |