Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.40 |
| ▸ | F2 | P00734 | 5/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547791 | 0.81 | CARM1 (0.43) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8545695 | 0.81 | SMN1; SMN2 (0.44) | ST14MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8545693 | 0.77 | SLC2A1 (0.39) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL10715281 | 0.75 | VEGFA (0.46) | ST14S1PR2MEN1KMT2AMITF | |
| SCHEMBL13479485 | 0.73 | IDO1 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL20938211 | 0.73 | IDO1 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL15472280 | 0.71 | NPBWR1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8546074 | 0.70 | F2 (0.41) | F2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8550856 | 0.70 | SLC1A3 (0.34) | ST14F2MEN1KMT2AMITF | |
| SCHEMBL31655464 | 0.70 | SOS1 (0.52) | ST14F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |