Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545695 | 0.81 | SMN1; SMN2 (0.44) | ST14ALDH1A1SMN1; SMN2AOC3MEN1 | |
| SCHEMBL8547791 | 0.77 | CARM1 (0.43) | ST14ALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL8544288 | 0.77 | ST14 (0.40) | ST14ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14217867 | 0.69 | ACHE (0.54) | SLC2A1ALDH1A1SMN1; SMN2HPGDHSD17B1 | |
| SCHEMBL8551347 | 0.69 | SLC6A4 (0.45) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL8546637 | 0.69 | CYP2A6 (0.57) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8545697 | 0.69 | ST14 (0.42) | ST14ALDH1A1SMN1; SMN2HSD17B1HSD17B2 | |
| SCHEMBL10349728 | 0.69 | SLC2A1 (0.74) | SLC2A1ALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL12260797 | 0.68 | ENPP2 (0.59) | SLC2A1ALDH1A1SMN1; SMN2HPGDHSD17B1 | |
| SCHEMBL21585201 | 0.68 | AOC3 (0.55) | SLC2A1ALDH1A1AOC3PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |