Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544960 | 0.84 | PDE4D (0.58) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5617204 | 0.84 | HPGD (0.54) | HPGDKMT2APOLBRAB9ANPC1 | |
| SCHEMBL3661643 | 0.84 | HPGD (0.54) | HPGDKMT2APOLBRAB9ANPC1 | |
| SCHEMBL22133207 | 0.84 | HPGD (0.51) | HPGDKMT2APOLBRAB9ANPC1 | |
| SCHEMBL6488893 | 0.84 | NPC1 (0.62) | HPGDKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1850967 | 0.83 | HPGDS (0.55) | HPGDKMT2APOLBRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL27759786 | 0.83 | HPGD (0.52) | HPGDKMT2APOLBRAB9ANPC1 | |
| SCHEMBL6223780 | 0.81 | HPGD (0.51) | HPGDKMT2APOLBRAB9ANPC1 | |
| SCHEMBL28924750 | 0.81 | NPC1 (0.56) | HPGDKMT2APOLBRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL4670042 | 0.81 | RAB9A (0.52) | HPGDKMT2APOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |