Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544352 | 0.90 | — | — | |
| SCHEMBL7312302 | 0.82 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL27396106 | 0.82 | PIK3CA (0.34) | — | |
| SCHEMBL7306330 | 0.81 | — | — | |
| SCHEMBL9429563 | 0.79 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL7302782 | 0.77 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL7310859 | 0.76 | — | — | |
| SCHEMBL8546004 | 0.76 | — | — | |
| SCHEMBL9695758 | 0.76 | AGTR1 (0.54) | AGTR1 | |
| SCHEMBL9655980 | 0.75 | PPARG (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514198-B1 | 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group | GLAXO GROUP LTD (GB) | 1998-08-05 | — | — | EP | disclosed |
| US-5498722-A | HYPOTENSIVES | GLAXO GROUP (GB) | 1996-03-12 | — | — | US | disclosed |
| CN-1079223-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1993-12-08 | — | — | CN | disclosed |
| WO-1992020674-A1 | 1H-IMIDAZOL-1-YL-METHYL BENZOFURAN DERIVATIVES, WITH THE IMIDAZOLYL MOIETY BEING SUBSTITUTED BY A CYCLOALKYL GROUP | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514198-A1 | 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |