Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9221603 | 0.96 | TBXAS1 (0.55) | TBXAS1PLA2G4A | |
| SCHEMBL8538159 | 0.91 | TBXAS1 (0.50) | TBXAS1PLA2G4A | |
| SCHEMBL8544258 | 0.89 | TBXAS1 (0.47) | TBXAS1PLA2G4A | |
| Trifluoroacetic Acid SCHEMBL9034373 | 0.89 | TBXAS1 (0.49) | TBXAS1PLA2G4A | |
| SCHEMBL8544039 | 0.86 | TBXAS1 (0.52) | TBXAS1 | |
| SCHEMBL8543141 | 0.85 | TBXAS1 (0.46) | TBXAS1 | |
| SCHEMBL8541177 | 0.85 | TBXAS1 (0.54) | TBXAS1 | |
| SCHEMBL8537545 | 0.85 | CYP3A4 (0.47) | TBXAS1 | |
| SCHEMBL8580528 | 0.84 | TBXAS1 (0.51) | TBXAS1 | |
| SCHEMBL8544233 | 0.83 | TBXAS1 (0.50) | TBXAS1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | disclosed |