Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544039 | 0.84 | TBXAS1 (0.52) | TBXAS1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL8544402 | 0.84 | TBXAS1 (0.56) | TBXAS1 | |
| SCHEMBL8538159 | 0.82 | TBXAS1 (0.50) | TBXAS1HDAC3HDAC1CNR2LTA4H | |
| SCHEMBL8583670 | 0.81 | PTGDR2 (0.53) | TBXAS1CNR2LTA4HKDM4E | |
| SCHEMBL8544233 | 0.81 | TBXAS1 (0.50) | TBXAS1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL8544230 | 0.81 | TBXAS1 (0.50) | TBXAS1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL8543283 | 0.81 | TBXAS1 (0.51) | TBXAS1CNR2CNR1KDM4ECYP11B1 | |
| SCHEMBL8582873 | 0.81 | TRPM5 (0.41) | TBXAS1HDAC3CNR2LTA4HCNR1 | |
| Trifluoroacetic Acid SCHEMBL9221603 | 0.80 | TBXAS1 (0.55) | TBXAS1 | |
| SCHEMBL8544258 | 0.79 | TBXAS1 (0.47) | TBXAS1HDAC3HDAC1CNR2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | disclosed |