SCHEMBL8544499

SCHEMBL8544499

Cc1c(Cl)cnn(C)c1=O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 7/20 0.48
KAT2B Q92831 7/20 0.48
BPTF Q12830 5/20 0.46
ALDH1A1 P00352 3/20 0.44
HPGD P15428 1/20 0.44
BRD4 O60885 7/20 0.42
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PKM P14618 2/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL979278 0.80 KAT2B (0.60) BRD9KAT2BBPTFALDH1A1HPGD
SCHEMBL2642056 0.78 KAT2B (0.53) BRD9KAT2BBPTFALDH1A1HPGD
Hydrochloric Acid SCHEMBL17912386 0.78 KAT2B (0.58) BRD9KAT2BBPTFALDH1A1HPGD
SCHEMBL12497715 0.77 BRD4 (0.46) BRD9KAT2BBPTFALDH1A1HPGD
SCHEMBL17912381 0.77 KAT2B (0.47) BRD9KAT2BBPTFALDH1A1HPGD
SCHEMBL2642058 0.77 KAT2B (0.47) BRD9KAT2BBPTFALDH1A1HPGD
SCHEMBL4163687 0.77 KAT2B (0.47) BRD9KAT2BBPTFALDH1A1HPGD
SCHEMBL15282281 0.77 KAT2B (0.47) BRD9KAT2BBPTFALDH1A1HPGD
SCHEMBL14844549 0.75 ALDH1A1 (0.56) BRD9KAT2BBPTFALDH1A1HPGD
SCHEMBL14074017 0.74 KAT2B (0.58) BRD9KAT2BBPTFALDH1A1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720040-A1 SULFONAMIDE COMPOUNDS BENEFICIAL IN NEUROPROTECTIVE TREATMENT Lario Therapeutics Limited (GB) 2026-04-08 EP disclosed
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 WO disclosed
CN-113727972-B Novel hydrazone derivatives having terminal amine groups substituted with aryl or heteroaryl groups and use thereof 韩国科学技术研究院 2024-12-27 CN disclosed
WO-2024246522-A1 SULFONAMIDE COMPOUNDS BENEFICIAL IN NEUROPROTECTIVE TREATMENT LARIO THERAPEUTICS LIMITED (GB) 2024-12-05 WO disclosed
WO-2023020479-A1 PARP7 INHIBITOR AND APPLICATION THEREOF 重庆华森制药股份有限公司 2023-02-23 WO disclosed
CN-108558889-A Bu Luomo structural domain inhibitor 赛尔基因昆蒂赛尔研究公司 2018-09-21 CN disclosed
EP-0717734-B1 PYRIDAZINONE DERIVATIVES OR THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, AND ANTI-SHOCK AGENTS CONTAINING THEM ISHIHARA SANGYO KAISHA (JP) 1998-11-18 EP disclosed
US-5763439-A POTENTIATION ISHIHARA SANGYO KAISHA LTD. (JP) 1998-06-09 US disclosed
EP-0717734-A1 PYRIDAZINONE DERIVATIVES OR THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, AND ANTI-SHOCK AGENTS CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-06-26 EP disclosed
WO-1995007264-A1 PYRIDAZINONE DERIVATIVES OR THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, AND ANTI-SHOCK AGENTS CONTAINING THEM ISHIHARA SANGYO KAISHA LTD. (JP) 1995-03-16 WO disclosed