Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544653 | 1.00 | ERCC5 (0.49) | ERCC5FEN1PKMNPC1KDM2B | |
| SCHEMBL8544615 | 0.92 | CTSK (0.47) | ERCC5FEN1NPC1KDM2BRAB9A | |
| SCHEMBL8544621 | 0.92 | CTSK (0.47) | ERCC5FEN1NPC1KDM2BRAB9A | |
| SCHEMBL8548127 | 0.91 | MEN1 (0.51) | NPC1KDM2BRAB9AMEN1KMT2A | |
| SCHEMBL8548133 | 0.91 | MEN1 (0.51) | NPC1KDM2BRAB9AMEN1KMT2A | |
| SCHEMBL8545352 | 0.90 | KMT2A (0.46) | RAB9AMEN1KMT2ACTSK | |
| SCHEMBL8545349 | 0.90 | KMT2A (0.46) | RAB9AMEN1KMT2ACTSK | |
| SCHEMBL8543631 | 0.88 | SPHK1 (0.54) | KDM2BMEN1KMT2ALMNA | |
| SCHEMBL8543635 | 0.88 | SPHK1 (0.54) | KDM2BMEN1KMT2ALMNA | |
| SCHEMBL8543316 | 0.87 | CTSK (0.53) | NPC1RAB9AMEN1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |