Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 8/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545349 | 1.00 | KMT2A (0.46) | KMT2AALDH1A1MAPTCTSKCHRNB2 | |
| SCHEMBL8548486 | 0.90 | CTSK (0.46) | KMT2AALDH1A1MAPTCTSKMEN1 | |
| SCHEMBL8548482 | 0.90 | CTSK (0.46) | KMT2AALDH1A1MAPTCTSKMEN1 | |
| SCHEMBL8544653 | 0.90 | ERCC5 (0.49) | KMT2ACTSKMEN1RAB9A | |
| SCHEMBL8544642 | 0.90 | ERCC5 (0.49) | KMT2ACTSKMEN1RAB9A | |
| SCHEMBL8548133 | 0.89 | MEN1 (0.51) | KMT2AALDH1A1CTSKMEN1RAB9A | |
| SCHEMBL8548127 | 0.89 | MEN1 (0.51) | KMT2AALDH1A1CTSKMEN1RAB9A | |
| SCHEMBL8543631 | 0.86 | SPHK1 (0.54) | KMT2AALDH1A1MEN1SPHK1SPHK2 | |
| SCHEMBL8543635 | 0.86 | SPHK1 (0.54) | KMT2AALDH1A1MEN1SPHK1SPHK2 | |
| SCHEMBL8545355 | 0.86 | ALDH1A1 (0.51) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |