Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548127 | 1.00 | MEN1 (0.51) | MEN1KMT2ARAB9ANPC1CTSK | |
| SCHEMBL8544642 | 0.91 | ERCC5 (0.49) | MEN1KMT2ARAB9ANPC1CTSK | |
| SCHEMBL8544653 | 0.91 | ERCC5 (0.49) | MEN1KMT2ARAB9ANPC1CTSK | |
| SCHEMBL8549474 | 0.90 | CTSK (0.56) | CTSKALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8549483 | 0.90 | CTSK (0.56) | CTSKALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8545349 | 0.89 | KMT2A (0.46) | MEN1KMT2ARAB9ACTSKALDH1A1 | |
| SCHEMBL8545352 | 0.89 | KMT2A (0.46) | MEN1KMT2ARAB9ACTSKALDH1A1 | |
| SCHEMBL8543631 | 0.87 | SPHK1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8543635 | 0.87 | SPHK1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8546896 | 0.86 | ALDH1A1 (0.48) | KMT2ACTSKALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |