Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551450 | 0.94 | S1PR2 (0.47) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8543274 | 0.94 | S1PR2 (0.47) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8544062 | 0.94 | S1PR2 (0.47) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8550526 | 0.94 | S1PR2 (0.47) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8551534 | 0.94 | S1PR2 (0.47) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8552037 | 0.94 | S1PR2 (0.47) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8549440 | 0.94 | S1PR2 (0.47) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8551864 | 0.93 | THRB (0.50) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 | |
| Formamide SCHEMBL8546773 | 0.84 | S1PR1 (0.47) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL8546355 | 0.81 | ALDH1A1 (0.45) | THRBIDO1SMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |