Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514812 | 0.85 | ALDH1A1 (0.39) | GAAHDAC6ALDH1A1TSHRHPGD | |
| SCHEMBL17086067 | 0.83 | ALDH1A1 (0.41) | GAAHDAC6ALDH1A1TSHRHTT | |
| SCHEMBL8835734 | 0.83 | ALDH1A1 (0.49) | GAAHDAC6ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4018620 | 0.82 | GAA (0.43) | GAAALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL27701441 | 0.80 | POLB (0.42) | GAAHDAC6ALDH1A1TSHRHTT | |
| SCHEMBL8541907 | 0.78 | ALDH1A1 (0.44) | GAAALDH1A1HPGDHTTKDM4E | |
| SCHEMBL11789572 | 0.78 | ALDH1A1 (0.41) | GAAHDAC6ALDH1A1TSHRHTT | |
| SCHEMBL8779748 | 0.77 | TSHR (0.47) | GAAALDH1A1TSHRALOX15SMN1; SMN2 | |
| SCHEMBL31612303 | 0.77 | ALDH1A1 (0.40) | GAAHDAC6ALDH1A1TSHRHTT | |
| SCHEMBL26631742 | 0.76 | ALDH1A1 (0.47) | GAAHDAC6ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483881-B1 | 3-Amidoindolyl derivatives | MERRELL PHARMA INC (US) | 1998-01-21 | — | — | EP | disclosed |