Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | UBE2N | P61088 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.74 |
| ▸ | APP | P05067 | 9/20 | 0.71 |
| ▸ | ACHE | P22303 | 7/20 | 0.71 |
| ▸ | BCHE | P06276 | 5/20 | 0.71 |
| ▸ | CASP6 | P55212 | 1/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734758 | 0.90 | CASP6 (0.62) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL12175837 | 0.87 | RAD52 (1.00) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL16280667 | 0.86 | CASP6 (0.92) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL3636779 | 0.83 | ACHE (1.00) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8544714 | 0.80 | APP (0.72) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL23748460 | 0.79 | RAD52 (0.77) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL2590671 | 0.79 | RAD52 (0.82) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL2590855 | 0.79 | RAD52 (0.82) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL2583542 | 0.79 | RAD52 (0.82) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL3639768 | 0.79 | RAD52 (0.82) | RAD52KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020821-A1 | HETEROARYL DERIVATIVES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |