Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.53 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.53 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.53 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.53 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.53 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376523 | 0.93 | DHODH (0.49) | ALPLCYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL9370476 | 0.87 | HSD17B10 (0.47) | ALPLCYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL9376516 | 0.87 | CYP1A2 (0.51) | ALPLCYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL17595027 | 0.85 | ESR1 (0.56) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL9374446 | 0.83 | MCL1 (0.57) | KDM4EMCL1P4HTMMAPTL3MBTL1 | |
| SCHEMBL10387678 | 0.80 | LMNA (0.49) | CYP1A2CYP3A4KDM4EMCL1SMN1; SMN2 | |
| SCHEMBL9370649 | 0.79 | ESR1 (0.50) | KDM4EMCL1DHODHADORA3ALDH1A1 | |
| SCHEMBL17595320 | 0.79 | MCL1 (0.71) | ALPLMCL1SMN1; SMN2ADORA3MAPT | |
| SCHEMBL9370136 | 0.79 | MCL1 (0.52) | KDM4EMCL1P4HTMSMN1; SMN2MAPT | |
| SCHEMBL9823342 | 0.78 | CYP1A1 (0.63) | ALPLCYP1A1CYP1B1CYP1A2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191451-B1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2019-06-05 | — | — | EP | claimed |
| US-20170217889-A1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2017-08-03 | — | — | US | claimed |
| EP-3191451-A1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | Okinawa Institute of Science and Technology School Corporation (JP) | 2017-07-19 | — | — | EP | claimed |
| WO-2016038890-A1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2016-03-17 | — | — | WO | claimed |
| EP-0525825-B1 | Substituted dicarboxy pyridine compounds | EG & G WALLAC OY (FI) | 1998-12-09 | — | — | EP | disclosed |
| EP-0341298-B1 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES | BAXTER DIAGNOSTICS INC (US) | 1994-06-22 | — | — | EP | disclosed |
| EP-0195413-B1 | Substituted pyridine derivatives | BAXTER DIAGNOSTICS INC (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5252740-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1993-10-12 | — | — | US | disclosed |
| US-5245038-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0525825-A2 | Substituted dicarboxy pyridine compounds | Dade MicroScan Inc. (US) | 1993-02-03 | — | — | EP | disclosed |
| US-5116989-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1992-05-26 | — | — | US | disclosed |
| US-5106957-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5055578-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-5032677-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER INTERNATIONAL INC. (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0341298-A4 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES. | BAXTER INT (US) | 1990-02-20 | — | — | EP | disclosed |
| EP-0341298-A1 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES | Baxter Diagnostics Inc. (US) | 1989-11-15 | — | — | EP | disclosed |
| WO-1989004826-A1 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES | BAXTER INTERNATIONAL INC. (US) | 1989-06-01 | — | — | WO | disclosed |
| US-4761481-A | FLUORESCENT CHELATES, AMINE ACID COMPOUNDS | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0195413-A2 | Substituted pyridine derivatives | Baxter Diagnostics Inc. (US) | 1986-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217889-A1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | PDK2, PKD1, PDHA2 | ALPL 4241/4885CYP1A1 244/4885CYP1B1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.