Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | RXRB | P28702 | 2/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544888 | 1.00 | MAPK1 (0.60) | MAPK1NR1H4KMT2ARXRARXRB | |
| SCHEMBL28455017 | 0.91 | MAPK1 (0.51) | MAPK1NR1H4KMT2ARXRARXRB | |
| SCHEMBL28455013 | 0.91 | MAPK1 (0.51) | MAPK1NR1H4KMT2ARXRARXRB | |
| SCHEMBL834902 | 0.85 | NR1H4 (0.70) | MAPK1NR1H4KMT2ARXRARXRB | |
| SCHEMBL8652183 | 0.84 | LMNA (0.63) | MAPK1NR1H4KMT2ARXRARXRB | |
| SCHEMBL8540479 | 0.83 | MAPT (0.64) | KMT2ATSHRPOLBLMNAMAPT | |
| SCHEMBL15662189 | 0.83 | MAPK1 (0.76) | MAPK1KMT2ARXRARXRBPLA2G4B | |
| SCHEMBL6776836 | 0.83 | MAPT (0.64) | KMT2ATSHRPOLBLMNAMAPT | |
| SCHEMBL1304301 | 0.82 | MAPK1 (0.60) | MAPK1NR1H4KMT2ARXRARXRB | |
| SCHEMBL5151823 | 0.82 | MAPK1 (0.60) | MAPK1NR1H4KMT2ARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736078-B1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5474705-A | Electrooptical displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-12-12 | — | — | US | disclosed |