SCHEMBL8652183

SCHEMBL8652183

CC(O)COc1ccc(C(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.63
MAPK1 P28482 1/20 0.62
PLA2G4B P0C869 3/20 0.59
KMT2A Q03164 1/20 0.56
NR1H4 Q96RI1 2/20 0.56
POLB P06746 2/20 0.56
MAPT P10636 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
RXRA P19793 2/20 0.55
RXRB P28702 2/20 0.55
PKM P14618 1/20 0.55
SRD5A2 P31213 1/20 0.54
RARB P10826 1/20 0.54
TP53 P04637 1/20 0.53
TSHR P16473 1/20 0.53
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
NR4A1 P22736 1/20 0.51
NR4A2 P43354 1/20 0.51
NR4A3 Q92570 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13309703 0.95 RARB (0.61) LMNAMAPK1PLA2G4BKMT2ANR1H4
Benzoic Acid SCHEMBL7771041 0.89 LMNA (0.76) LMNAMAPK1PLA2G4BNR1H4POLB
SCHEMBL10592803 0.87 LMNA (0.60) LMNAMAPK1KMT2APOLBMAPT
SCHEMBL834902 0.87 NR1H4 (0.70) LMNAMAPK1PLA2G4BKMT2ANR1H4
SCHEMBL11702315 0.85 MAPT (0.77) LMNAPOLBMAPTNPSR1RAB9A
SCHEMBL9741323 0.85 PLA2G4B (0.71) LMNAMAPK1PLA2G4BNR1H4POLB
SCHEMBL7768531 0.85 PKM (0.58) LMNAMAPK1PLA2G4BNR1H4POLB
SCHEMBL4200509 0.84 LMNA (0.68) LMNAMAPK1POLBMAPTSMN1; SMN2
SCHEMBL5949941 0.84 LMNA (0.78) LMNAPOLBMAPTNPSR1TSHR
SCHEMBL5151823 0.84 MAPK1 (0.60) LMNAMAPK1PLA2G4BKMT2ANR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0221293-B1 7,8,9,10-Tetrahydro-6-oxo-6H-dibenzo[b,d]pyranyloxy-propanes PENNWALT CORPORATION (US) 1989-03-08 EP claimed
US-11252960-B2 Antibacterial composition including benzoic acid ester and methods of inhibiting bacterial growth utilizing the same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2022-02-22 US disclosed
US-11224221-B2 2022-01-18 US disclosed
EP-0570230-B1 External preparation for skin SHISEIDO CO LTD (JP) 1998-09-30 EP disclosed
EP-0262809-B1 Pyrimidinylphenyl ester compound TEIKOKU CHEM IND CO LTD (JP) 1994-05-11 EP disclosed
US-4980082-A DISPLAY ELEMENTS; HIGH SPEED RESPONSE TO ELECTRICAL FIELDS SEIKO INSTRUMENTS INC. (JP) 1990-12-25 US disclosed
EP-0262809-A1 Pyrimidinylphenyl ester compound TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) 1988-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11252960-B2 Antibacterial composition including benzoic acid ester and methods of inhibiting bacterial growth utilizing the same DBI, BCAT1, TBCA LMNA 2808/4885MAPK1 2690/4885PLA2G4B 3660/4885
US-11224221-B2 TBCA, SPOUT1, BPGM LMNA 2701/4885MAPK1 3605/4885PLA2G4B 3484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.