Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024946 | 0.83 | TSHR (0.47) | LMNATAAR1CYP2A6 | |
| SCHEMBL4841473 | 0.82 | CALM1 (0.57) | CALM1LTA4HLMNATAAR1SIGMAR1 | |
| SCHEMBL27961331 | 0.81 | SLC6A2 (0.45) | TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13496520 | 0.80 | CALM1 (0.55) | CALM1LTA4HLMNAKEAP1NFE2L2 | |
| SCHEMBL8767137 | 0.80 | CALM1 (0.55) | CALM1LTA4HLMNAKEAP1NFE2L2 | |
| SCHEMBL10515119 | 0.78 | CALM1 (0.52) | CALM1LTA4HLMNAKEAP1NFE2L2 | |
| SCHEMBL14127281 | 0.78 | — | — | |
| SCHEMBL3728 | 0.78 | — | — | |
| SCHEMBL1551 | 0.78 | — | — | |
| Benzene SCHEMBL22288204 | 0.78 | TAAR1 (0.48) | LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1136213-C | New benzothiophene, benzofuran and indole compounds, preparation method therefor and medicine composition containing same | ɪά��ʵ���� | 2004-01-28 | — | — | CN | disclosed |
| CN-1293192-A | New benzothiophene, benzofuran and indole compounds, preparation method therefor and medicine composition containing same | ADIR (FR) | 2001-05-02 | — | — | CN | disclosed |
| CN-1241176-A | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER (US) | 2000-01-12 | — | — | CN | disclosed |
| EP-0837848-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001536-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1997-01-16 | — | — | WO | disclosed |