SCHEMBL8767137

SCHEMBL8767137

CC(c1ccccc1)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.55
LTA4H P09960 2/20 0.48
LMNA P02545 1/20 0.45
TAAR1 Q96RJ0 7/20 0.43
SIGMAR1 Q99720 3/20 0.43
SLC18A2 Q05940 1/20 0.43
IDH1 O75874 1/20 0.42
ACACB O00763 1/20 0.42
ACACA Q13085 1/20 0.42
SLC6A2 P23975 2/20 0.41
MAOA P21397 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
CYP2A6 P11509 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
ESR1 P03372 1/20 0.41
PDCD1 Q15116 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771606 0.88 CYP3A4 (0.54) CALM1LTA4HLMNATAAR1SIGMAR1
SCHEMBL4841473 0.84 CALM1 (0.57) CALM1LTA4HLMNATAAR1SIGMAR1
SCHEMBL8643448 0.83 ESR1 (0.55) LMNATAAR1ESR1PDCD1ESR2
SCHEMBL444227 0.82 TP53 (0.56) LMNATAAR1CYP2A6ESR1PDCD1
SCHEMBL28059422 0.81 MAOA (0.46) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL9499016 0.81 CALM1 (0.60) CALM1LTA4HLMNAIDH1SLC6A2
SCHEMBL10515119 0.80 CALM1 (0.52) CALM1LTA4HLMNATAAR1SIGMAR1
SCHEMBL8544893 0.80 CALM1 (0.52) CALM1LTA4HLMNATAAR1SIGMAR1
SCHEMBL6547023 0.80 PTGS1 (0.55) LMNASIGMAR1ESR1
SCHEMBL6895362 0.80 CALM1 (0.52) CALM1LTA4HLMNAIDH1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0171081-B1 OIL-FILLED CAPACITOR Nippon Petrochemicals Company, Limited (JP) 1991-12-04 EP claimed
US-4591948-A DIELECTRIC PLASTIC FILM MATERIAL IMPREGNATED WITH 1-PHENYL-1-(BENZYLPHENYL) ETHANE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-05-27 US claimed
EP-0171081-A2 Oil-filled capacitor Nippon Petrochemicals Company, Limited (JP) 1986-02-12 EP claimed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US claimed
EP-0570599-B1 METALLIZED PLASTIC FILM CAPACITOR NIPPON PETROCHEMICALS CO LTD (JP) 1997-08-20 EP disclosed
US-5384684-A Impregnation with insulating oils of triglycerides with aromatic esters NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1995-01-24 US disclosed
EP-0570599-A1 METALLIZED PLASTIC FILM CAPACITOR NIPPON PETROCHEMICALS CO., LTD. (JP) 1993-11-24 EP disclosed
EP-0171081-B1 OIL-FILLED CAPACITOR Nippon Petrochemicals Company, Limited (JP) 1991-12-04 EP disclosed
US-4591948-A DIELECTRIC PLASTIC FILM MATERIAL IMPREGNATED WITH 1-PHENYL-1-(BENZYLPHENYL) ETHANE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-05-27 US disclosed
US-4591948-A DIELECTRIC PLASTIC FILM MATERIAL IMPREGNATED WITH 1-PHENYL-1-(BENZYLPHENYL) ETHANE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-05-27 US disclosed
EP-0171081-A2 Oil-filled capacitor Nippon Petrochemicals Company, Limited (JP) 1986-02-12 EP disclosed
EP-0171081-A2 Oil-filled capacitor Nippon Petrochemicals Company, Limited (JP) 1986-02-12 EP disclosed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed