Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954494 | 0.93 | TSHR (0.52) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL8544893 | 0.83 | CALM1 (0.52) | TAAR1LMNACYP2A6 | |
| SCHEMBL2491352 | 0.78 | TP53 (0.56) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL9774407 | 0.76 | LPL (0.43) | L3MBTL1HPGDTP53ALDH1A1LMNA | |
| SCHEMBL1415320 | 0.75 | ESR1 (0.38) | TDP1TAAR1LMNA | |
| SCHEMBL18242410 | 0.75 | L3MBTL1 (0.52) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL139408 | 0.74 | L3MBTL1 (0.56) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL500563 | 0.74 | TSHR (0.56) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL9596832 | 0.73 | PTGS1 (0.53) | TSHRAKR1C3AKR1C2LMNA | |
| SCHEMBL9596827 | 0.73 | PTGS1 (0.53) | TSHRAKR1C3AKR1C2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803957-A | Benzylic glycoside derivatives and methods of use | THERACOS INC | 2015-07-29 | — | — | CN | disclosed |