Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538922 | 0.94 | PSEN1 (0.44) | RECQLHTR6PSEN1PSEN2APH1B | |
| SCHEMBL8540330 | 0.88 | PSEN1 (0.48) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8540926 | 0.79 | KIF11 (0.40) | SIRT2ALDH1A1LMNAMAPT | |
| SCHEMBL8541589 | 0.76 | ACSS2 (0.39) | ALDH1A1LMNAMAPT | |
| SCHEMBL8540088 | 0.74 | PSEN1 (0.46) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2202154 | 0.74 | CYP11B1 (0.40) | SIRT2ALDH1A1LMNA | |
| SCHEMBL8540763 | 0.72 | PSEN1 (0.39) | RECQLSRCHTR6PSEN1PSEN2 | |
| SCHEMBL8540756 | 0.72 | PSEN1 (0.39) | RECQLSRCHTR6PSEN1PSEN2 | |
| SCHEMBL8540560 | 0.72 | PSEN1 (0.47) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5688715 | 0.71 | SIRT2 (0.40) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820989-A1 | IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |