Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541589 | 0.86 | ACSS2 (0.39) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL8540330 | 0.81 | PSEN1 (0.48) | GAA | |
| SCHEMBL21636129 | 0.79 | SIRT2 (0.35) | SIRT2ENPP2ACSS2 | |
| SCHEMBL8545171 | 0.79 | RECQL (0.40) | ALDH1A1MAPTLMNASIRT2 | |
| SCHEMBL2202154 | 0.78 | CYP11B1 (0.40) | KDM4EALDH1A1LMNASIRT2ENPP2 | |
| SCHEMBL8541131 | 0.77 | — | — | |
| SCHEMBL8538922 | 0.77 | PSEN1 (0.44) | GAAHTT | |
| SCHEMBL5688715 | 0.75 | SIRT2 (0.40) | NPC1RAB9ASIRT2ENPP2 | |
| SCHEMBL8540731 | 0.75 | KIF11 (0.46) | KIF11KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL5682208 | 0.75 | AKR1C3 (0.40) | LMNANPC1RAB9ATSHRSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820989-A1 | IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |