Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 15/20 | 0.34 |
| ▸ | CA12 | O43570 | 14/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547101 | 0.80 | CA9 (0.53) | KMT2ATDP1CA9CA12L3MBTL1 | |
| SCHEMBL16126846 | 0.80 | CA9 (0.37) | KMT2APTGDR2CA9CA12L3MBTL1 | |
| SCHEMBL8550846 | 0.78 | CA9 (0.38) | KMT2APTGDR2CA9CA12L3MBTL1 | |
| SCHEMBL8550940 | 0.73 | CA9 (0.59) | KMT2ATDP1CA9CA12CA1 | |
| SCHEMBL1369709 | 0.71 | PTGDR2 (0.42) | KMT2ATDP1PTGDR2CA9CA12 | |
| SCHEMBL17191865 | 0.70 | PTGDR2 (0.38) | PTGDR2CA9CA12L3MBTL1ABCC9 | |
| SCHEMBL8546709 | 0.68 | CA9 (0.53) | KMT2ATDP1CA9CA12ABCC9 | |
| SCHEMBL7335719 | 0.68 | PTGDR2 (0.44) | PTGDR2CA9CA12CA1CA2 | |
| SCHEMBL7337341 | 0.64 | PTGDR2 (0.44) | KMT2APTGDR2CA9CA12L3MBTL1 | |
| SCHEMBL8731341 | 0.64 | ALDH1A1 (0.50) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752990-B1 | BENZISOTHIAZOLES DERIVATIVES AS INHIBITORS OF 5-LIPOXYGENASE BIOSYNTHESIS | PFIZER (US) | 1998-08-05 | — | — | EP | disclosed |
| US-5665749-A | Benzisothiazoles derivatives as inhibitors of 5-lipoxygenase biosynthesis | PFIZER INC. (US) | 1997-09-09 | — | — | US | disclosed |
| US-5160363-A | For sugarbeets | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-03 | — | — | US | disclosed |
| EP-0422031-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| WO-1989010921-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-16 | — | — | WO | disclosed |