Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RHOC | P08134 | 1/20 | 0.30 |
| ▸ | RHOA | P61586 | 1/20 | 0.30 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973054 | 0.82 | LTA4H (0.34) | — | |
| SCHEMBL9147011 | 0.79 | MAPT (0.56) | MAPTUSP2TSHRSMN1; SMN2NPC1 | |
| SCHEMBL8542603 | 0.79 | TSHR (0.34) | MAPTUSP2TSHRSMN1; SMN2NPC1 | |
| SCHEMBL9578539 | 0.79 | MAPT (0.51) | MAPTUSP2TSHRSMN1; SMN2NPC1 | |
| SCHEMBL7557746 | 0.78 | ESR2 (0.34) | — | |
| SCHEMBL8545570 | 0.77 | DGAT1 (0.34) | MAPTUSP2TSHRSMN1; SMN2NPC1 | |
| SCHEMBL6966971 | 0.76 | NPC1 (0.33) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8545314 | 0.75 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL9187564 | 0.75 | MAPT (0.48) | MAPTUSP2TSHRSMN1; SMN2NPC1 | |
| SCHEMBL8540319 | 0.75 | NPC1 (0.32) | MAPTSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736078-B1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5474705-A | Electrooptical displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-12-12 | — | — | US | disclosed |