Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543272 | 0.95 | EDNRB (0.60) | EDNRBEDNRA | |
| SCHEMBL8856544 | 0.95 | EDNRB (0.60) | EDNRBEDNRA | |
| SCHEMBL8545164 | 0.91 | EDNRB (0.51) | EDNRBEDNRA | |
| SCHEMBL8546146 | 0.87 | EDNRB (0.58) | EDNRBEDNRA | |
| SCHEMBL8546889 | 0.86 | LMNA (0.51) | EDNRBEDNRA | |
| SCHEMBL8540948 | 0.85 | EDNRA (0.72) | EDNRBEDNRA | |
| SCHEMBL8539775 | 0.84 | LMNA (0.51) | EDNRBEDNRA | |
| SCHEMBL8592047 | 0.84 | EDNRB (0.59) | EDNRBEDNRA | |
| SCHEMBL8546008 | 0.83 | EDNRB (0.60) | EDNRBEDNRA | |
| SCHEMBL8856895 | 0.83 | EDNRB (0.71) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800389-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| US-5684032-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC, ANTIASTHMATIC AGENTS AND RESPIRATORY DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0800389-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996018393-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-20 | — | — | WO | disclosed |