Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 17/20 | 0.53 |
| ▸ | EDNRB | P24530 | 16/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540470 | 0.88 | EDNRB (0.66) | EDNRAEDNRB | |
| SCHEMBL8592047 | 0.88 | EDNRB (0.59) | EDNRAEDNRB | |
| SCHEMBL8546889 | 0.87 | LMNA (0.51) | EDNRAEDNRB | |
| SCHEMBL7492499 | 0.83 | EDNRA (0.59) | EDNRAEDNRBABCB11 | |
| SCHEMBL8545866 | 0.82 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL8543285 | 0.81 | EDNRB (0.69) | EDNRAEDNRB | |
| SCHEMBL8546008 | 0.81 | EDNRB (0.60) | EDNRAEDNRB | |
| SCHEMBL8539775 | 0.81 | LMNA (0.51) | EDNRAEDNRB | |
| SCHEMBL8616220 | 0.81 | MAPT (0.51) | EDNRAEDNRB | |
| SCHEMBL8590639 | 0.80 | EDNRA (0.64) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800389-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| US-5684032-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC, ANTIASTHMATIC AGENTS AND RESPIRATORY DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0800389-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996018393-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-20 | — | — | WO | disclosed |