⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4755774 | 0.98 | ELANE (0.37) | — | |
| SCHEMBL14801073 | 0.84 | ELANE (0.34) | — | |
| SCHEMBL402280 | 0.80 | — | — | |
| SCHEMBL5611586 | 0.80 | — | — | |
| SCHEMBL4308472 | 0.79 | GLS (0.38) | — | |
| SCHEMBL11214735 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL9713098 | 0.78 | CYP3A4 (0.49) | — | |
| SCHEMBL1259259 | 0.78 | MEN1 (0.51) | — | |
| SCHEMBL9601627 | 0.77 | — | — | |
| SCHEMBL3644950 | 0.75 | KMT2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193864-B | Pyrazole-1-carboxylate derivatives, process for producing the same, and process for producing pyrazole derivatives | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2011-12-07 | — | — | CN | claimed |
| CN-101193864-A | Pyrazole-1-carboxylate derivatives, process for producing the same, and process for producing pyrazole derivatives | SAGAMI CHEM RES (JP) | 2008-06-04 | — | — | CN | claimed |
| EP-0658547-B1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEM CORP (JP) | 1998-03-11 | — | — | EP | claimed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | claimed |
| JP-7258219-A | — | — | None | — | — | JP | disclosed |
| EP-4504341-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | Shy Therapeutics LLC (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196975-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2023-10-12 | — | — | WO | disclosed |
| EP-2768509-A1 | SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS | Glaxosmithkline LLC (US) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013059587-A1 | SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2013-04-25 | — | — | WO | disclosed |
| CN-101193864-B | Pyrazole-1-carboxylate derivatives, process for producing the same, and process for producing pyrazole derivatives | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2011-12-07 | — | — | CN | disclosed |
| CN-101193864-A | Pyrazole-1-carboxylate derivatives, process for producing the same, and process for producing pyrazole derivatives | SAGAMI CHEM RES (JP) | 2008-06-04 | — | — | CN | disclosed |
| EP-0658547-B1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEM CORP (JP) | 1998-03-11 | — | — | EP | disclosed |
| EP-0658547-B1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEM CORP (JP) | 1998-03-11 | — | — | EP | disclosed |
| JP-H07258219-A | N-PYRAZOLYLCARBAMATE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT | MITSUBISHI CHEM CORP | 1995-10-09 | — | — | JP | disclosed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0043798-A1 | Pyrazolyl carbamates and their use as pesticides | CIBA-GEIGY AG (CH) | 1982-01-13 | — | — | EP | disclosed |
| EP-0043798-A1 | Pyrazolyl carbamates and their use as pesticides | CIBA-GEIGY AG (CH) | 1982-01-13 | — | — | EP | disclosed |
| EP-0043798-A1 | Pyrazolyl carbamates and their use as pesticides | CIBA-GEIGY AG (CH) | 1982-01-13 | — | — | EP | disclosed |