SCHEMBL402280

SCHEMBL402280

NC(=O)Nn1cccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8545489 0.80
SCHEMBL3912844 0.78
SCHEMBL4517927 0.78
Hydrochloric Acid SCHEMBL4755774 0.78 ELANE (0.37)
SCHEMBL5611586 0.78
Hydrochloric Acid SCHEMBL28556948 0.77 NOS1 (0.47)
SCHEMBL5967559 0.74 NOS1 (0.39)
SCHEMBL4308472 0.74 GLS (0.38)
SCHEMBL11214735 0.74 ALDH1A1 (0.40)
SCHEMBL3644950 0.74 KMT2A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111808259-B 3D printing silicone rubber and preparation method and application thereof 四川大学 2021-10-12 CN claimed
CN-110964162-B Pyrazole ureido-based polyureaurethane and preparation method and application thereof 中国科学院化学研究所 2021-03-16 CN claimed
CN-111808259-A 3D printing silicone rubber and preparation method and application thereof 四川大学 2020-10-23 CN claimed
CN-111699180-B Pyrazole N-linked carbamoyl cyclohexyl acid as LPA antagonist 百时美施贵宝公司 2024-11-29 CN disclosed
EP-3616695-B1 CEFTOLOZANE/TAZOBACTAM FOR TREATING INTRAPULMONARY INFECTIONS MERCK SHARP & DOHME LLC (US) 2024-10-23 EP disclosed
US-20240307427-A1 REMDESIVIR COCRYSTAL, COMPOSITIONS AND METHODS THEREOF VERSITECH LIMITED (CN) 2024-09-19 US disclosed
CN-118638154-A Ruidexiwei eutectic, composition and method thereof 港大科桥有限公司 2024-09-13 CN disclosed
CN-113307772-B Human plasma kallikrein inhibitors 拜奥克里斯特制药公司 2024-06-28 CN disclosed
US-20240150295-A1 HUMAN PLASMA KALLIKREIN INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2024-05-09 US disclosed
US-20240150296-A1 HUMAN PLASMA KALLIKREIN INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2024-05-09 US disclosed
CN-117843913-A Bipyrazole-based metal coordination self-repairing polyurethane elastomer and preparation method thereof 浙江大学 2024-04-09 CN disclosed
US-5086184-A Herbicides DOWELANCO (US) 1992-02-04 US disclosed
US-4943634-A HERBICIDES ELI LILLY AND COMPANY (US) 1990-07-24 US disclosed
US-4801718-A HERBICIDES ELI LILLY AND COMPANY (US) 1989-01-31 US disclosed
US-4636243-A HERBICIDES ISOXAZOLES ELI LILLY AND COMPANY (US) 1987-01-13 US disclosed
US-4523940-A ADDING METAL COMPLEX SALTS OF SUBSTITUTED PYRAZOLE COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1985-06-18 US disclosed
US-4515625-A HERBICIDES ELI LILLY AND COMPANY (US) 1985-05-07 US disclosed
EP-0049071-B1 N-ARYLBENZAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1984-12-19 EP disclosed
US-4416683-A HERBICIDES ELI LILLY AND COMPANY (US) 1983-11-22 US disclosed
EP-0049071-A1 N-arylbenzamide derivatives ELI LILLY AND COMPANY (US) 1982-04-07 EP disclosed