Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924952 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TSHRTYMSALOX15TDP1 | |
| SCHEMBL27801935 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TSHRTYMSALOX15TDP1 | |
| SCHEMBL855562 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TSHRTYMSALOX15TDP1 | |
| SCHEMBL4924942 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRTYMSALOX15TDP1 | |
| SCHEMBL9284604 | 0.74 | TYMS (0.47) | ALDH1A1TSHRTYMSALOX15TDP1 | |
| SCHEMBL853556 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TSHRTYMSALOX15TDP1 | |
| SCHEMBL855592 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TSHRTYMSALOX15TDP1 | |
| SCHEMBL855131 | 0.74 | TSHR (0.57) | ALDH1A1TSHR | |
| SCHEMBL30523205 | 0.74 | ALOX15 (0.37) | ALDH1A1TSHRTYMSALOX15TDP1 | |
| SCHEMBL855653 | 0.74 | ALOX15 (0.37) | ALDH1A1TSHRTYMSALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433933-B1 | PRODUCTION METHOD OF TRI- OR TETRAHALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL CO (JP) | 2019-05-08 | — | — | EP | disclosed |
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |