Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | AGER | Q15109 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821042 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL8542675 | 0.88 | KDM4E (0.56) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL7822651 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL7818617 | 0.83 | CES2 (0.50) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL9635664 | 0.82 | KDM4E (0.80) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL2212405 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL27673772 | 0.77 | CES2 (0.74) | ALDH1A1TSHRNPSR1KMT2ACES2 | |
| SCHEMBL7821603 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| Quinolinic Acid SCHEMBL27486714 | 0.75 | KDM4E (0.96) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| Quinolinic Acid SCHEMBL69230 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1MAPTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639183-B1 | NITROGEN OXIDES OF AZA- AND DIAZA-ANTHRACENEDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA (IT) | 1998-07-01 | — | — | EP | disclosed |
| EP-0639183-A1 | NITROGEN OXIDES OF AZA- AND DIAZA-ANTHRACENEDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992015566-A1 | NITROGEN OXIDES OF AZA- AND DIAZA-ANTHRACENEDIONE DERIVATIVES AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-09-17 | — | — | WO | disclosed |