Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545077 | 0.87 | TSHR (0.53) | TSHRALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL12303132 | 0.82 | KDM4E (0.60) | TSHRALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL8546271 | 0.81 | MEN1 (0.48) | TSHRALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL8545841 | 0.79 | MCL1 (0.56) | TSHRALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL3232932 | 0.78 | MEN1 (0.64) | ALDH1A1KDM4EHSD17B10LMNANPC1 | |
| SCHEMBL31388315 | 0.78 | MEN1 (0.64) | ALDH1A1KDM4EHSD17B10LMNANPC1 | |
| Hydrochloric Acid SCHEMBL8551040 | 0.78 | MCL1 (0.55) | TSHRALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL17243832 | 0.77 | TSHR (0.53) | TSHRALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL21003759 | 0.77 | NPC1 (0.56) | TSHRALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL8551031 | 0.77 | NPC1 (0.53) | TSHRALDH1A1KDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525825-B1 | Substituted dicarboxy pyridine compounds | EG & G WALLAC OY (FI) | 1998-12-09 | — | — | EP | disclosed |
| EP-0195413-B1 | Substituted pyridine derivatives | BAXTER DIAGNOSTICS INC (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0525825-A2 | Substituted dicarboxy pyridine compounds | Dade MicroScan Inc. (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4761481-A | FLUORESCENT CHELATES, AMINE ACID COMPOUNDS | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0195413-A2 | Substituted pyridine derivatives | Baxter Diagnostics Inc. (US) | 1986-09-24 | — | — | EP | disclosed |