Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545077 | 0.81 | TSHR (0.53) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL8545773 | 0.81 | TSHR (0.53) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL7902881 | 0.79 | LTB4R (0.44) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL8545841 | 0.78 | MCL1 (0.56) | NPC1RAB9AHPGDSMN1; SMN2CTSV | |
| Hydrochloric Acid SCHEMBL8551040 | 0.77 | MCL1 (0.55) | NPC1RAB9AHPGDSMN1; SMN2CTSV | |
| SCHEMBL8551031 | 0.76 | NPC1 (0.53) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL12303132 | 0.74 | KDM4E (0.60) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL4271285 | 0.73 | KDM4E (0.52) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL7908882 | 0.72 | ALDH1A1 (0.36) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29066085 | 0.72 | MTNR1A (0.62) | MEN1KMT2ANPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525825-B1 | Substituted dicarboxy pyridine compounds | EG & G WALLAC OY (FI) | 1998-12-09 | — | — | EP | disclosed |
| EP-0195413-B1 | Substituted pyridine derivatives | BAXTER DIAGNOSTICS INC (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0525825-A2 | Substituted dicarboxy pyridine compounds | Dade MicroScan Inc. (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4761481-A | FLUORESCENT CHELATES, AMINE ACID COMPOUNDS | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0195413-A2 | Substituted pyridine derivatives | Baxter Diagnostics Inc. (US) | 1986-09-24 | — | — | EP | disclosed |