Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8551040 | 0.99 | MCL1 (0.55) | MCL1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8551031 | 0.90 | NPC1 (0.53) | MCL1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL19180309 | 0.84 | ALDH1A1 (0.62) | MCL1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8545077 | 0.81 | TSHR (0.53) | NPC1RAB9AHPGDSMN1; SMN2CTSV | |
| SCHEMBL12303132 | 0.81 | KDM4E (0.60) | NPC1RAB9AHPGDSMN1; SMN2CTSV | |
| SCHEMBL21003759 | 0.79 | NPC1 (0.56) | NPC1RAB9AHPGDSMN1; SMN2CTSV | |
| SCHEMBL8545773 | 0.79 | TSHR (0.53) | NPC1RAB9AHPGDSMN1; SMN2TSHR | |
| SCHEMBL9374446 | 0.78 | MCL1 (0.57) | MCL1KDM4EMRGPRX4SRD5A2MAPT | |
| SCHEMBL17037225 | 0.78 | PDE4A (0.53) | HPGDSMN1; SMN2CTSVCTSLPDE4A | |
| SCHEMBL8546271 | 0.78 | MEN1 (0.48) | NPC1RAB9AHPGDSMN1; SMN2CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525825-B1 | Substituted dicarboxy pyridine compounds | EG & G WALLAC OY (FI) | 1998-12-09 | — | — | EP | disclosed |
| EP-0195413-B1 | Substituted pyridine derivatives | BAXTER DIAGNOSTICS INC (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0525825-A2 | Substituted dicarboxy pyridine compounds | Dade MicroScan Inc. (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4761481-A | FLUORESCENT CHELATES, AMINE ACID COMPOUNDS | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0195413-A2 | Substituted pyridine derivatives | Baxter Diagnostics Inc. (US) | 1986-09-24 | — | — | EP | disclosed |