Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 9/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.43 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545815 | 0.93 | MAOB (0.54) | GPR132MAOBNR4A2 | |
| SCHEMBL8549666 | 0.90 | GPR132 (0.60) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL8547558 | 0.88 | SMPD1 (0.52) | MAOBNR4A2 | |
| SCHEMBL8545746 | 0.86 | GPR132 (0.51) | GPR132MAOBNR4A2 | |
| SCHEMBL8549981 | 0.86 | MRGPRX4 (0.52) | GPR132MAOBNR4A2 | |
| SCHEMBL7910951 | 0.86 | GPR132 (0.49) | GPR132MAOB | |
| SCHEMBL7910954 | 0.86 | GPR132 (0.49) | GPR132MAOB | |
| SCHEMBL8546398 | 0.85 | FFAR1 (0.46) | GPR132MAOBNR4A2 | |
| SCHEMBL8549929 | 0.85 | — | — | |
| SCHEMBL8545507 | 0.85 | MAOB (0.42) | GPR132MAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |