Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 5/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545815 | 0.87 | MAOB (0.54) | GPR132PTPN1NR4A2MAOB | |
| SCHEMBL8545786 | 0.86 | GPR132 (0.52) | GPR132NR4A2MAOB | |
| SCHEMBL7907403 | 0.86 | GPR132 (0.48) | GPR132CYSLTR1CYSLTR2 | |
| SCHEMBL7907400 | 0.86 | GPR132 (0.48) | GPR132CYSLTR1CYSLTR2 | |
| SCHEMBL8547664 | 0.86 | CYSLTR1 (0.41) | GPR132CYSLTR1CYSLTR2NR4A2MAOB | |
| SCHEMBL8549666 | 0.85 | GPR132 (0.60) | GPR132 | |
| SCHEMBL8545743 | 0.83 | GPR132 (0.47) | GPR132CYSLTR1MAPK14SMOPARP10 | |
| SCHEMBL8547558 | 0.82 | SMPD1 (0.52) | PTPN1NR4A2MAOB | |
| SCHEMBL8549981 | 0.82 | MRGPRX4 (0.52) | GPR132CYSLTR1CYSLTR2NR4A2MAOB | |
| SCHEMBL8546699 | 0.82 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |